μ-conotoxin-PIIIA
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μ-conotoxin-PIIIA

μ-conotoxin-PIIIA – Ion Channels and Transporters μ-Conotoxin PIIIA (mu-conotoxin PIIIA) is a conotoxin that has been isolated from the venom of the cone Conus purpurascens. μ-conotoxin PIIIA demonstrates a higher affinity for the mammalian muscle sodium channel Nav1.4 (IC50 ~ 44 nM) than for the CNS Nav1.2 subtype (IC50 ~ 640 nm). μ-Conotoxin PIIIA blocks […]

Technical Specifications

Sequence:pQ-RLCCGF(Hyp)KSCRSRQCK(Hyp)HRCC-NH2 (Cys4-Cys16; Cys5-Cys21; Cys11-Cys22)
Purity:> 95% (by HPLC)
Counter-Ion:TFA Salts
Delivery Format:Lyophilized



Product Description & Background

μ-conotoxin-PIIIA – Ion Channels and Transporters

μ-Conotoxin PIIIA (mu-conotoxin PIIIA) is a conotoxin that has been isolated from the venom of the cone Conus purpurascens. μ-conotoxin PIIIA demonstrates a higher affinity for the mammalian muscle sodium channel Nav1.4 (IC50 ~ 44 nM) than for the CNS Nav1.2 subtype (IC50 ~ 640 nm). μ-Conotoxin PIIIA blocks more irreversibly amphibian muscle sodium channels than mammalian ones.

 

Technical specification

 KD20 peptide Sequence : pQ-RLCCGF(Hyp)KSCRSRQCK(Hyp)HRCC-NH2 (Cys4-Cys16; Cys5-Cys21; Cys11-Cys22)
 KD20 peptide MW : 2605.06 g/mol
 KD20 peptide Purity : > 95%
 KD20 peptide Counter-Ion : TFA Salts
Peptide library synthesis KD20 peptide Delivery format : Lyophilized

Price

 

Product Size Price € Price $
08CON006-0.1 mg 0.1 mg 165€ 198$
08CON006-0.5 mg 0.5 mg 440€ 528$

If you’d like to learn more about this toxin, visit our product page on our Genpabio website—Our sister company specializing in the synthesis of complex toxins.