Leiurotoxin-1 Dab7 – Ion Channels and Transporters
Leiuorotoxin-Dab7 (Lei-Dab7) is a mutated version of Leiurotoxin, a peptide identified from the venom of the scorpion Leiurus quinquestriatus hebraeus. The Dab amino acid in position 7 confers to this compound a high selectivity for SK2 channels among other channels. Lei-Dab7 exhibits > 200 fold selectivity for SK2 over SK1, SK3, IK, Kv and Kir channels. The IC50 for SK2 is about 3 nM.
Technical specification
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Sequence : | H-AFCNLRZCQLSCRSLGLLGKCIGDKCECVKH (avec Z=Dab)-NH2 (Cys3-Cys21; Cys8-Cys26; Cys12-Cys28) |
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MW : | 3392.12 g/mol |
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Purity : | > 95% |
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Counter-Ion : | TFA Salts |
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Delivery format : | Lyophilized |
Price
| Product | Size | Price € | Price $ |
| LED01-0.1 mg | 0.1 mg | 242€ | 291$ |
| LED01-0.5 mg | 0.5 mg | 726€ | 872$ |
| LED01-5 x 0.01 mg | 5 x 0.01 mg | 215€ | 258$ |
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