Iberiotoxin
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Iberiotoxin

Iberiotoxin – Ion Channels and Transporters Iberiotoxin (IbTx) is a toxin that was originally isolated from Buthus tamulus scorpion venom. Iberiotoxin inhibits selectively the high conductance Ca2+-activated K+ channel (KCa1.1) at nanomolar concentrations (IC50 ~2 nM). This toxin does not affect other types of calcium-dependent or voltage-dependent K+ channels. Iberiotoxin is a valuable tool to […]

Technical Specifications

Sequence:pQ-FTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ-OH (Cys7-Cys28; Cys13-Cys33; Cys17-Cys35)
Purity:> 95% (by HPLC)
Counter-Ion:TFA Salts
Delivery Format:Lyophilized



Product Description & Background

Iberiotoxin – Ion Channels and Transporters

Iberiotoxin (IbTx) is a toxin that was originally isolated from Buthus tamulus scorpion venom. Iberiotoxin inhibits selectively the high conductance Ca2+-activated K+ channel (KCa1.1) at nanomolar concentrations (IC50 ~2 nM). This toxin does not affect other types of calcium-dependent or voltage-dependent K+ channels. Iberiotoxin is a valuable tool to study specifically Maxi-K channels.

 

Technical specification

 KD20 peptide Sequence : pQ-FTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ-OH (Cys7-Cys28; Cys13-Cys33; Cys17-Cys35)
 KD20 peptide MW : 4230.85 g/mol
 KD20 peptide Purity : > 95%
 KD20 peptide Counter-Ion : TFA Salts
Peptide library synthesis KD20 peptide Delivery format : Lyophilized

Price

 

Product Size Price € Price $
12IBX001-0.5 mg 0.5 mg 429€ 515$
12IBX001-1 mg 1 mg 605€ 726$
12IBX001-5 x 0.01 mg 5 x 0.01 mg 132€ 159$

If you’d like to learn more about this toxin, visit our product page on our Genpabio website—Our sister company specializing in the synthesis of complex toxins.