TAT – GluR23Y

TAT – GluR23Y – TAT Conjugated Peptides TAT-GluR23Y is a cell penetrating peptide that inhibits phosphorylation of AMPA receptor endocytosis. Recent studies have shown that AMPA receptor endocytosis, which is a cellular mechanism underlying the formation of LTD, plays a critical role in facilitating initial extinction of learned fear. Tat-Glur23Y can block regulated AMPA and […]

Technical Specifications

Sequence:	`H-YGRKKRRQRRRYKEGYNVYG-OH`
Purity:	> 95% (by HPLC)
Counter-Ion:	TFA Salts
Delivery Format:	Lyophilized

Product Description & Background

TAT – GluR23Y – TAT Conjugated Peptides

TAT-GluR23Y is a cell penetrating peptide that inhibits phosphorylation of AMPA receptor endocytosis. Recent studies have shown that AMPA receptor endocytosis, which is a cellular mechanism underlying the formation of LTD, plays a critical role in facilitating initial extinction of learned fear. Tat-Glur23Y can block regulated AMPA and thereby prevents long-term depression (LTD) in structures such as the nucleus accumbens and dorsal hippocampus.

Technical specification

	Sequence :	H-YGRKKRRQRRRYKEGYNVYG-OH
	MW :	2.632.4 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized

Price

Product	Size	Price €	Price $
CRB1001142-0.5 mg	0.5 mg	141€	170$
CRB1001142-1 mg	1 mg	193€	232$