Pentapeptide-31
Signal pentapeptide for skin ECM renewal and regenerative anti-aging
Pentapeptide-31 is a synthetic signal pentapeptide that supports skin regeneration and ECM structural renewal by activating fibroblast and keratinocyte signaling pathways. It promotes the synthesis of structural ECM components and accelerates skin cell turnover, improving overall skin quality. Suitable for anti-aging, resurfacing, and regenerative formulations where skin renewal and ECM remodeling are primary objectives.
Main characteristics
Pentapeptide-31 provides a clean, synthetic signal peptide option for ECM renewal with a straightforward AGELS sequence. Its small molecular weight facilitates dermal penetration. Compatible with most anti-aging serum and cream bases. Stable at pH 5.0–7.5. Produced via SPPS to ≥95% purity (HPLC + MS).
Applications
- Anti-aging skin renewal serums and treatments
- Formulations targeting skin texture improvement
- ombination peptide anti-aging systems
- Post-peel and regenerative skincare
- Research in fibroblast and keratinocyte activation via signal pentapeptides
Technical specification
| Sequency : | H-AGELS-NH2 | |
| INCI name | Pentapeptide-31 | |
| MW : | 474.51 g/mol | |
| Purity : | > 95% | |
| Counter-Ion : | TFA Salts | |
| Delivery format : | Lyophilized | |
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CAS number : | 1232137-75-5 |
TFA removal service available (acetate or HCl exchange)
Price
| Product | Size | Price € |
Price $ |
| SB379-20mg | 20 mg | 351.82 | 422.19 |
| SB379-50mg | 50 mg | 527.73 | 633.28 |
| SB379-100mg | 100 mg | 703.64 | 844.37 |
| SB379-500mg | 500 mg | 1372.10 | 1646.52 |
Custom Cosmetic Peptides Services
If your target is not listed, we offer custom Cosmetic Peptides design and synthesis. Whether you require sequence optimization, specific modifications, or larger production quantities, our team can support your project. Submit your project details and we will provide a personalized proposal.
Analytical Documentation Included
A Certificate of Analysis (CoA), MS analysis, and HPLC purity report are provided with every batch.
Research Use Only
For research and laboratory use only. Not for human consumption or therapeutic use.

