Palmitoyl Tetrapeptide-7
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Palmitoyl Tetrapeptide-7

Palmitoyl Tetrapeptide-7 / Rigin Reduces inflammation and supports matrix repair Palmitoyl Tetrapeptide-7 (Rigin?) is derived from the GQPR sequence of the Fc fragment of IgG immunoglobulin. It suppresses IL-6 secretion by keratinocytes and fibroblasts, the primary pro-inflammatory cytokine driving ‘inflammaging’ and MMP-mediated collagen degradation. Most commonly formulated with Palmitoyl Tripeptide-1 as the widely used Matrixyl […]

Technical Specifications

Sequence:Pal-GQPR-OH
Purity:694.91 g/mol (by HPLC)
Counter-Ion:TFA Salts
Delivery Format:Lyophilized

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Product Description & Background

Palmitoyl Tetrapeptide-7 / Rigin

Reduces inflammation and supports matrix repair

Palmitoyl Tetrapeptide-7 (Rigin?) is derived from the GQPR sequence of the Fc fragment of IgG immunoglobulin. It suppresses IL-6 secretion by keratinocytes and fibroblasts, the primary pro-inflammatory cytokine driving ‘inflammaging’ and MMP-mediated collagen degradation. Most commonly formulated with Palmitoyl Tripeptide-1 as the widely used Matrixyl 3000? complex, where it plays the anti-inflammatory protective role.

Main characteristics

Palmitoyl Tetrapeptide-7 helps reduce the low-grade inflammation associated with skin aging, protecting the extracellular matrix (ECM) from degradation. By reducing IL-6, it slows the MMP cascade that destroys collagen and elastin. In Matrixyl 3000, it pairs with Pal-Tripeptide-1 (which builds new collagen) for a protect dual strategy. Stable at pH 4.5–7.5. Produced via SPPS to ≥95% purity (HPLC + MS).

Applications
  • Anti-aging serums and moisturizer
  • Anti-inflammatory anti-aging formulations
  • Sensitive and mature skin anti-aging products
  • UV-protective and post-UV calming formulations
  • Research in IL-6-mediated inflammaging and MMP regulation

 

Technical specification

Sequency : Pal-GQPR-OH
INCI name Palmitoyl Tetrapeptide-7
MW : 694.91 g/mol
Purity : > 95%
Counter-Ion : TFA Salts
Delivery format : Lyophilized
CAS number : 221227-05-0

TFA removal service available (acetate or HCl exchange)

Price

 

Product Size Price €
 Price $
SB373-20mg 20 mg 246.27 295.53
SB373-50mg 50 mg 369.41 443.29
SB373-100mg 100 mg 492.55 591.06
SB373-500mg 500 mg 960.47 1152.57

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Custom Cosmetic Peptides Services

If your target is not listed, we offer custom Cosmetic Peptides design and synthesis. Whether you require sequence optimization, specific modifications, or larger production quantities, our team can support your project. Submit your project details and we will provide a personalized proposal.

 

Analytical Documentation Included
A Certificate of Analysis (CoA), MS analysis, and HPLC purity report are provided with every batch.

 

Research Use Only
For research and laboratory use only. Not for human consumption or therapeutic use.

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