Neurokinin B (human, porcine)

Neurokinin B (human, porcine) – Neuroscience Peptides Neurokinin B (NKB) is a member of the tachykinin family of peptides that include substance P (SP), neurokinin A (NKA), endokinins and haemokinins. NKB is encoded by TAC3 in humans and Tac2 in rodents and along with the neuropeptide kisspeptin plays an essential role as gatekeeper of puberty. […]

Technical Specifications

Sequence:	`H-DMHDFFVGLM-NH2`
Purity:	> 95% (by HPLC)
Counter-Ion:	TFA Salts
Delivery Format:	Lyophilized

Product Description & Background

Neurokinin B (human, porcine) – Neuroscience Peptides

Neurokinin B (NKB) is a member of the tachykinin family of peptides that include substance P (SP), neurokinin A (NKA), endokinins and haemokinins. NKB is encoded by TAC3 in humans and Tac2 in rodents and along with the neuropeptide kisspeptin plays an essential role as gatekeeper of puberty. NKB plays a stimulatory role in luteinising hormone (LH) release in a number of species, likely mediated via the secretion of gonadotropin-releasing hormone (GnRH) in a kisspeptin-dependent manner (NKB appears to play a critical role in the control of kisspeptin release). NKB may contribute to the regulation of reproductive functions by metabolic cues. NKB binds with highest affinity to the G-protein coupled neurokinin-3 receptor NK3R also known as tachykinin receptor 3 (TACR3)

Technical specification

	Sequence :	H-DMHDFFVGLM-NH2
	MW :	1.209.5 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized

Price

Product	Size	Price €	Price $
CRB1000581-0.5 mg	0.5 mg	141€	170$
CRB1000581-1 mg	1 mg	193€	232$