Cyclo(RGDfK)

Cyclo(RGDfK) – Immunology – Antigens/Epitotes/Pools/Librairies The cyclic pentapeptide cyclo(Arg-Gly-Asp-[D-Phe]-Lys) is a highly potent and selective inhibitor for the alphavβ3 integrin receptor. A related compound, cyclo(Arg-Gly-Asp-[D-Phe]-Val), is a promising anticancer drug candidate- it inhibits angiogenesis and induces apoptosis in vascular cells. Cyclic RGD-containing peptides are selective antagonists of integrins, proteins that play important roles in cell-cell […]

Technical Specifications

Sequence:	`[LacN(0,5)]RGD(dF)K`
Purity:	> 95% (by HPLC)
Counter-Ion:	TFA Salts
Delivery Format:	Lyophilized

Product Description & Background

Cyclo(RGDfK) – Immunology – Antigens/Epitotes/Pools/Librairies

The cyclic pentapeptide cyclo(Arg-Gly-Asp-[D-Phe]-Lys) is a highly potent and selective inhibitor for the alphavβ3 integrin receptor. A related compound, cyclo(Arg-Gly-Asp-[D-Phe]-Val), is a promising anticancer drug candidate- it inhibits angiogenesis and induces apoptosis in vascular cells. Cyclic RGD-containing peptides are selective antagonists of integrins, proteins that play important roles in cell-cell and cell-matrix interactions. In a suitably labelled form, these peptides may serve as useful tools for diagnostic imaging and peptide targeted therapy of some types of cancer.

Technical specification

	Sequence :	[LacN(0,5)]RGD(dF)K
	MW :	603.3 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized

Price

Product	Size	Price €	Price $
CRB1001046-1 mg	1 mg	385€	462$