Acetyl Tetrapeptide-5 / Eyeseryl
Acetyl Tetrapeptide-5 is a specialized tetrapeptide designed for the delicate periorbital region. It reduces vascular permeability and enhances lymphatic microcirculation, preventing interstitial fluid accumulation in the lower eyelid compartment. The peptide also inhibits glycation of collagen and reduces hemoglobin oxidation products responsible for dark circles. Clinical studies demonstrate significant reduction in under-eye puffiness and dark circle appearance. It is a benchmark active ingredient for eye contour formulations in skincare.
Main characteristics
Acetyl Tetrapeptide 5‘s dual action: draining excess fluid while simultaneously protecting periorbital collagen from glycation. It is uniquely effective for the multi-factorial problem of under-eye appearance. It is well-tolerated on the delicate periorbital skin. Stable in aqueous formulations and compatible with most eye contour bases. Produced via SPPS to ≥95% purity (HPLC + MS). Often combined with Dipeptide-2 (Val-Trp) for synergistic lymphatic drainage.
Applications
- Eye contour serums and creams targeting under-eye bags and puffiness
- Anti-dark circle formulations
- Periorbital lifting treatments
- Combination formulas with Dipeptide-2 for enhanced drainage effect
- Research in lymphatic microcirculation and periorbital vascular biology
Technical specification
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Sequency : | Ac-Beta-AHSH-OH |
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INCI name | Acetyl Tetrapeptide-5 |
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MW : | 492.21 g/mol |
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Purity : | > 95% |
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Counter-Ion : | TFA Salts |
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Delivery format : | Lyophilized |
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CAS number : | 820959-17-9 |
TFA removal service available (acetate or HCl exchange)
Price
| Product | Size | Price € |
Price $ |
| SB354-20mg | 20 mg | 246.27 | 295.53 |
| SB354-50mg | 50 mg | 369.41 | 443.29 |
| SB354-100mg | 100 mg | 492.55 | 591.06 |
| SB354-500mg | 500 mg | 960.47 | 1152.57 |
Custom Cosmetic Peptides Services
If your target is not listed, we offer custom Cosmetic Peptides design and synthesis. Whether you require sequence optimization, specific modifications, or larger production quantities, our team can support your project. Submit your project details and we will provide a personalized proposal.
Analytical Documentation Included
A Certificate of Analysis (CoA), MS analysis, and HPLC purity report are provided with every batch.
Research Use Only
For research and laboratory use only. Not for human consumption or therapeutic use.