Acetyl Octapeptide-3
Neurotransmitter Inhibitor
Acetyl Octapeptide-3 (SNAP-8) is an 8-amino acid extension of Argireline featuring two additional C-terminal residues (Ala-Asp), providing enhanced SNAP-25 competitive inhibition with greater binding efficiency at the SNARE complex. Clinical formulation studies suggest wrinkle depth reductions with regular use. Particularly effective on deep expression lines and forehead creases. Used in premium anti-aging serums and targeted wrinkle treatment concentrates.
Main characteristics
Acetyl Octapeptide-3 shares Argireline’s mechanism of competing with the N-terminal domain of SNAP-25 for integration into the SNARE complex, but the two additional residues improve the fit and duration of competitive binding. It is stable at pH 4.5–7.0 and compatible with most serum and cream bases. Often combined with Argireline for complementary coverage of the SNARE complex inhibition. Produced via SPPS to ≥95% purity (HPLC + MS).
Applications
- Premium anti-wrinkle serums targeting deep expression lines
- Forehead and periorbital wrinkle treatments
- Combination formulas with Argireline for dual-mechanism botox-like effect
- Research on SNARE complex dynamics and neuromuscular peptide inhibitors
Technical specification
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Sequency : | Ac-EEMQRRAD-NH2 |
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INCI name | Acetyl Octapeptide-3 |
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MW : | 1074.49 g/mol |
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Purity : | > 95% |
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Counter-Ion : | TFA Salts |
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Delivery format : | Lyophilized |
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CAS number : | 868844-74-0 |
TFA removal service available (acetate or HCl exchange)
Price
| Product | Size | Price € |
Price $ |
| SB351-20mg | 20 mg | 271.32 | 325.58 |
| SB351-50mg | 50 mg | 406.98 | 488.38 |
| SB351-100mg | 100 mg | 542.64 | 651.17 |
| SB351-500mg | 500 mg | 1058.15 | 1269.78 |
Custom Cosmetic Peptides Services
If your target is not listed, we offer custom Cosmetic Peptides design and synthesis. Whether you require sequence optimization, specific modifications, or larger production quantities, our team can support your project. Submit your project details and we will provide a personalized proposal.
Analytical Documentation Included
A Certificate of Analysis (CoA), MS analysis, and HPLC purity report are provided with every batch.
Research Use Only
For research and laboratory use only. Not for human consumption or therapeutic use.