Intracellular Sigma Peptide

Intracellular Sigma Peptide – Other Categories Intracellular Sigma peptide is a membrane-permeable peptide mimetic of protein tyrosine phosphatase sigma (PTPσ) wedge. PTPσ is a neural receptor that binds with very high affinity to chondroitin sulfate proteoglycans (CSPGs). Inhibition of this interaction has been shown to promote regeneration of damaged nerves and improve nerve function in […]

Technical Specifications

Sequence:	`H-GRKKRRQRRRCDMAEHMERLKANDSLKLSQEYESI-NH2`
Purity:	> 95% (by HPLC)
Counter-Ion:	TFA Salts
Delivery Format:	Lyophilized

Product Description & Background

Intracellular Sigma Peptide – Other Categories

Intracellular Sigma peptide is a membrane-permeable peptide mimetic of protein tyrosine phosphatase sigma (PTPσ) wedge. PTPσ is a neural receptor that binds with very high affinity to chondroitin sulfate proteoglycans (CSPGs). Inhibition of this interaction has been shown to promote regeneration of damaged nerves and improve nerve function in animal models. ISP has a protein transduction domain from HIV’s trans-activating regulatory protein (Tat). This domain allows facilitates membrane-penetration.

Technical specification

	Sequence :	H-GRKKRRQRRRCDMAEHMERLKANDSLKLSQEYESI-NH2
	MW :	4.316.2 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized

Price

Product	Size	Price €	Price $
CRB1001355-0.5 mg	0.5 mg	282€	339$
CRB1001355-1 mg	1 mg	385€	462$